The Gebel el-Haridi, an area of cliffs on the east bank of the Nile just north of modern Akhmim, was the focus of three seasons of survey sponsored by the Egypt Exploration Society and partially funded by Truman State University in the 1990s. This paper, the result in part of research conducted during a sabbatical year, discusses the Ptolemaic and Roman quarries at the site as well as an enigmatic building constructed in front of one of these quarries, which fits the elements of an Early Christian monastic settlement.